The impact of age and gut microbiota on Th17 and Tfh cells in K/BxN autoimmune arthritis

The impact of age and gut microbiota on Th17 and Tfh cells in K/BxN autoimmune arthritis

Abstract Background Age is an important risk factor for rheumatoid arthritis (RA), which often develops in middle age. However, how age-associated changes in immunity impact RA is poorly understood. Gut microbiota are known to be involved in the pathogenesis of RA, but the effects of microbiota in o...

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Bibliographic Details
Main Authors: Fei Teng, Krysta M. Felix, C. Pierce Bradley, Debdut Naskar, Heqing Ma, Walid A. Raslan, Hsin-Jung Joyce Wu
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis
Age
Gut microbiota
Tfh
Th17
Animal model
Online Access:http://link.springer.com/article/10.1186/s13075-017-1398-6

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http://link.springer.com/article/10.1186/s13075-017-1398-6

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