The impact of age and gut microbiota on Th17 and Tfh cells in K/BxN autoimmune arthritis
Abstract Background Age is an important risk factor for rheumatoid arthritis (RA), which often develops in middle age. However, how age-associated changes in immunity impact RA is poorly understood. Gut microbiota are known to be involved in the pathogenesis of RA, but the effects of microbiota in o...
Main Authors: | Fei Teng, Krysta M. Felix, C. Pierce Bradley, Debdut Naskar, Heqing Ma, Walid A. Raslan, Hsin-Jung Joyce Wu |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-08-01
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Series: | Arthritis Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13075-017-1398-6 |
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