Functional analysis of the cathepsin-like cysteine protease genes in adult Brugia malayi using RNA interference.

Cathepsin-like enzymes have been identified as potential targets for drug or vaccine development in many parasites, as their functions appear to be essential in a variety of important biological processes within the host, such as molting, cuticle remodeling, embryogenesis, feeding and immune evasion...

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Bibliographic Details
Main Authors: Louise Ford, Jun Zhang, Jing Liu, Sarwar Hashmi, Juliet A Fuhrman, Yelena Oksov, Sara Lustigman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2634747?pdf=render