Inflammasome activation negatively regulates MyD88-IRF7 type I IFN signaling and anti-malaria immunity

Inflammasome activation negatively regulates MyD88-IRF7 type I IFN signaling and anti-malaria immunity

The inflammasome is an essential component of inflammatory processes and the host response to infection. Here the authors show that inflammasome activation modulates MyD88-IRF7 type I IFN signalling and anti-malaria immunity.

Bibliographic Details
Main Authors: Xiao Yu, Yang Du, Chunmei Cai, Baowei Cai, Motao Zhu, Changsheng Xing, Peng Tan, Meng Lin, Jian Wu, Jian Li, Mingjun Wang, Helen Y. Wang, Xin-zhuan Su, Rong-Fu Wang
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07384-7

Internet

https://doi.org/10.1038/s41467-018-07384-7

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