Mammalian Taste Bud Cells Utilize Extragemmal 5-Hydroxy-L-Tryptophan to Biosynthesize the Neurotransmitter Serotonin

Mammalian Taste Bud Cells Utilize Extragemmal 5-Hydroxy-L-Tryptophan to Biosynthesize the Neurotransmitter Serotonin

Serotonin or 5-hydroxytryptamine (5-HT) is an important neurotransmitter that is found in mammalian taste buds and can regulate the output of intragemmal signaling networks onto afferent nerve fibers. However, it is unclear how 5-HT is produced, synthesized locally inside taste buds or absorbed from...

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Bibliographic Details
Main Authors: Hong-Ru Pan, Miao Tian, Jian-Bo Xue, Song-Min Li, Xiao-Cui Luo, Xiao Huang, Zhen-Huang Chen, Liquan Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neurotransmitter
biosynthesis
tryptophan hydroxylase
gene knockout
transportation
signal transmission
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00461/full

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https://www.frontiersin.org/article/10.3389/fncel.2018.00461/full

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