Downregulation of HLA Class I Renders Inflammatory Neutrophils More Susceptible to NK Cell-Induced Apoptosis

Downregulation of HLA Class I Renders Inflammatory Neutrophils More Susceptible to NK Cell-Induced Apoptosis

Neutrophils are potent effector cells and contain a battery of harmful substances and degrading enzymes. A silent neutrophil death, i.e., apoptosis, is therefore of importance to avoid damage to the surrounding tissue and to enable termination of the acute inflammatory process. There is a pile of ev...

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Bibliographic Details
Main Authors: Elin Bernson, Karin Christenson, Silvia Pesce, Malin Pasanen, Emanuela Marcenaro, Simona Sivori, Fredrik B. Thorén
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
neutrophil
NK cell
HLA class I
immunoregulation
neutrophil apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02444/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02444/full

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