Analgesic and Anticancer Activity of Benzoxazole Clubbed 2-Pyrrolidinones as Novel Inhibitors of Monoacylglycerol Lipase

Analgesic and Anticancer Activity of Benzoxazole Clubbed 2-Pyrrolidinones as Novel Inhibitors of Monoacylglycerol Lipase

Ten benzoxazole clubbed 2-pyrrolidinones (<b>11</b>–<b>20</b>) as human monoacylglycerol lipase inhibitors were designed on the criteria fulfilling the structural requirements and on the basis of previously reported inhibitors. The designed, synthesized, and characterized com...

Full description

Bibliographic Details
Main Authors: Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Mir Mohammad Shahroz, Hemant Kumar Sharma, Yassine Riadi, Md Quamrul Hassan
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
analgesic
anticancer
pyrrolidin-2-one
benzoxazole
MAGL inhibitors
molecular docking
Online Access:https://www.mdpi.com/1420-3049/26/8/2389

Internet

https://www.mdpi.com/1420-3049/26/8/2389

Similar Items