An artemisinin derivative of praziquantel as an orally active antischistosomal agent.

Schistosomiasis is a major health problem in tropical and sub-tropical areas caused by species of trematode belonging to the genus Schistosoma. The treatment and control of this disease has been relying on the use of a single drug praziquantel. However, the drug resistance concern urged the developm...

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Bibliographic Details
Main Authors: Lanlan Dong, Wenwen Duan, Jinglei Chen, Huan Sun, Chunhua Qiao, Chao-ming Xia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4227710?pdf=render