Favipiravir (T-705) inhibits Junín virus infection and reduces mortality in a guinea pig model of Argentine hemorrhagic fever.

Favipiravir (T-705) inhibits Junín virus infection and reduces mortality in a guinea pig model of Argentine hemorrhagic fever.

Junín virus (JUNV), the etiologic agent of Argentine hemorrhagic fever (AHF), is classified by the NIAID and CDC as a Category A priority pathogen. Presently, antiviral therapy for AHF is limited to immune plasma, which is readily available only in the endemic regions of Argentina. T-705 (favipiravi...

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Bibliographic Details
Main Authors: Brian B Gowen, Terry L Juelich, Eric J Sefing, Trevor Brasel, Jennifer K Smith, Lihong Zhang, Bersabeh Tigabu, Terence E Hill, Tatyana Yun, Colette Pietzsch, Yousuke Furuta, Alexander N Freiberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3873268?pdf=render

Internet

http://europepmc.org/articles/PMC3873268?pdf=render

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