Preceding Administration of Minocycline Suppresses Plastic Changes in Cortical Excitatory Propagation in the Model Rat With Partial Infraorbital Nerve Ligation

Preceding Administration of Minocycline Suppresses Plastic Changes in Cortical Excitatory Propagation in the Model Rat With Partial Infraorbital Nerve Ligation

Neuropathic pain is known to be attributable to the injured nerve, a postoperative problem induced by surgery. The infraorbital nerve (ION), a branch of the trigeminal nerve, innervates to the facial and oral regions and conveys somatosensory information to the central nervous system. The partial li...

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Bibliographic Details
Main Authors: Manabu Zama, Satoshi Fujita, Yuka Nakaya, Morio Tonogi, Masayuki Kobayashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neurology
Subjects:
insular cortex
somatosensory cortex
orofacial pain
referred pain
microglia
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01150/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.01150/full

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