The feasibility of incorporating Vpx into lentiviral gene therapy vectors

The feasibility of incorporating Vpx into lentiviral gene therapy vectors

While current antiretroviral therapy has significantly improved, challenges still remain in life-long targeting of HIV-1 reservoirs. Lentiviral gene therapy has the potential to deliver protective genes into the HIV-1 reservoir. However, inefficient reverse transcription (RT) occurs in HIV-1 reservo...

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Bibliographic Details
Main Authors: Samantha A McAllery, Chantelle L Ahlenstiel, Kazuo Suzuki, Geoff P Symonds, Anthony D Kelleher, Stuart G Turville
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050117300323

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http://www.sciencedirect.com/science/article/pii/S2329050117300323

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