Myosin Activators

Inotropes historically all increased intra-cellular calcium levels and they commonly causedintracellular Ca2+ overload and triggered malignant arrhythmias. The myosin activators, such as Omecamtiv Mecarbil (OM), increase myosin activity and function, and modify acto-myosin interaction through calciu...

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Bibliographic Details
Main Authors: Giuseppe MC Rosano, Piotr Ponikowski
Format: Article
Language:English
Published: Barcaray International 2019-01-01
Series:International Cardiovascular Forum Journal
Subjects:
Online Access:https://icfjournal.org/index.php/icfj/article/view/611/pdf