Huntingtin interacting proteins are genetic modifiers of neurodegeneration.

Huntingtin interacting proteins are genetic modifiers of neurodegeneration.

Huntington's disease (HD) is a fatal neurodegenerative condition caused by expansion of the polyglutamine tract in the huntingtin (Htt) protein. Neuronal toxicity in HD is thought to be, at least in part, a consequence of protein interactions involving mutant Htt. We therefore hypothesized that...

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Bibliographic Details
Main Authors: Linda S Kaltenbach, Eliana Romero, Robert R Becklin, Rakesh Chettier, Russell Bell, Amit Phansalkar, Andrew Strand, Cameron Torcassi, Justin Savage, Anthony Hurlburt, Guang-Ho Cha, Lubna Ukani, Cindy Lou Chepanoske, Yuejun Zhen, Sudhir Sahasrabudhe, James Olson, Cornelia Kurschner, Lisa M Ellerby, John M Peltier, Juan Botas, Robert E Hughes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1866352?pdf=render

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http://europepmc.org/articles/PMC1866352?pdf=render

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