The WldS gene modestly prolongs survival in the SOD1G93A fALS mouse

The WldS gene modestly prolongs survival in the SOD1G93A fALS mouse

The “slow Wallerian degeneration” (WldS) gene is neuroprotective in numerous models of axonal degeneration. Axonal degeneration is an early feature of disease progression in the SOD1G93A mouse, a widely used model of familial amyotrophic lateral sclerosis (fALS). We crossed the WldS mouse with the S...

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Bibliographic Details
Main Authors: Lindsey R. Fischer, Deborah G. Culver, Albert A. Davis, Philip Tennant, Minsheng Wang, Michael Coleman, Seneshaw Asress, Robert Adalbert, Guillermo M. Alexander, Jonathan D. Glass
Format: Article
Language:English
Published: Elsevier 2005-06-01
Series:Neurobiology of Disease
Subjects:
Axonal degeneration
Amyotrophic lateral sclerosis
ALS
SOD1
WldS
Wallerian degeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105000227

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http://www.sciencedirect.com/science/article/pii/S0969996105000227

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