Ribosomal 18S rRNA base pairs with mRNA during eukaryotic translation initiation

Ribosomal 18S rRNA base pairs with mRNA during eukaryotic translation initiation

Prokaryotic translation initiation involves mRNA-ribosomal RNA base pairing interactions. Here, the authors provide evidence for a similar base pairing interactions occurring between the human h4 mRNA and helix 16 of the small subunit rRNA to position the correct AUG codon in the decoding site.

Bibliographic Details
Main Authors: Franck Martin, Jean-François Ménétret, Angelita Simonetti, Alexander G. Myasnikov, Quentin Vicens, Lydia Prongidi-Fix, S. Kundhavai Natchiar, Bruno P. Klaholz, Gilbert Eriani
Format: Article
Language:English
Published: Nature Publishing Group 2016-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12622

Internet

https://doi.org/10.1038/ncomms12622

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