Substance P signalling in primary motor cortex facilitates motor learning in rats.

Among the genes that are up-regulated in response to a reaching training in rats, Tachykinin 1 (Tac1)-a gene that encodes the neuropeptide Substance P (Sub P)-shows an especially strong expression. Using Real-Time RT-PCR, a detailed time-course of Tac1 expression could be defined: a significant peak...

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Bibliographic Details
Main Authors: Benjamin Hertler, Jonas Aurel Hosp, Manuel Buitrago Blanco, Andreas Rüdiger Luft
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5744944?pdf=render