Human papillomavirus type 16 antagonizes IRF6 regulation of IL-1β.

Human papillomavirus type 16 antagonizes IRF6 regulation of IL-1β.

Human papillomavirus type 16 (HPV16) and other oncoviruses have been shown to block innate immune responses and to persist in the host. However, to avoid viral persistence, the immune response attempts to clear the infection. IL-1β is a powerful cytokine produced when viral motifs are sensed by inna...

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Bibliographic Details
Main Authors: Michelle Ainouze, Pauline Rochefort, Peggy Parroche, Guillaume Roblot, Issam Tout, François Briat, Claudia Zannetti, Marie Marotel, Nadege Goutagny, Philip Auron, Alexandra Traverse-Glehen, Aude Lunel-Potencier, Francois Golfier, Murielle Masson, Alexis Robitaille, Massimo Tommasino, Christine Carreira, Thierry Walzer, Thomas Henry, Katia Zanier, Gilles Trave, Uzma Ayesha Hasan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007158

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https://doi.org/10.1371/journal.ppat.1007158

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