Imaging Atherosclerotic Plaque Inflammation via Folate Receptor Targeting Using a Novel F-Folate Radiotracer
Folate receptor β (FR-β) is overexpressed on activated, but not resting, macrophages involved in a variety of inflammatory and autoimmune diseases. A pivotal step in atherogenesis is the subendothelial accumulation of macrophages. In nascent lesions, they coordinate the scavenging of lipids and cell...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi - SAGE Publishing
2014-03-01
|
Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2013.00074 |