IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells

IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells

Abstract Background Natural killer (NK) cells are an emerging new tool for cancer immunotherapy. To develop NK cell therapeutics from peripheral blood mononuclear cells (PBMCs) of healthy donors, substantial expansion of primary NK cells is necessary because of the very low number of these cells in...

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Bibliographic Details
Main Authors: Yeon Ho Choi, Eun Jin Lim, Se Wha Kim, Yong Wha Moon, Kyung Soon Park, Hee-Jung An
Format: Article
Language:English
Published: BMJ Publishing Group 2019-07-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Natural killer (NK) cells
Natural killer cell receptor
Interleukin (IL)-15
Interleukin (IL)-27
Interferon-gamma
Online Access:http://link.springer.com/article/10.1186/s40425-019-0652-7

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http://link.springer.com/article/10.1186/s40425-019-0652-7

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