Hippocampal ornithine decarboxylase/spermidine pathway mediates H2S-alleviated cognitive impairment in diabetic rats: Involving enhancment of hippocampal autophagic flux

Introduction: We have previously demonstrated the antagonistic role of hydrogen sulfide (H2S) in the cognitive dysfunction of streptozotocin (STZ)-induced diabetic rats. It has been confirmed that the impaired hippocampal autophagic flux has a key role in the pathogenesis of cognitive impairment and...

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Bibliographic Details
Main Authors: Xuan Kang, Cheng Li, Yan Xie, Ling-Li He, Fan Xiao, Ke-Bin Zhan, Yi-Yun Tang, Xiang Li, Xiao-Qing Tang
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Journal of Advanced Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123220301168