The Molecular Fingerprint of High Grade Serous Ovarian Cancer Reflects Its Fallopian Tube Origin

The Molecular Fingerprint of High Grade Serous Ovarian Cancer Reflects Its Fallopian Tube Origin

High grade serous ovarian cancer (HGSC), the most lethal and frequent type of epithelial ovarian cancer (EOC), has poor long term prognosis due to a combination of factors: late detection, great metastatic potential and the capacity to develop resistance to available therapeutic drugs. Furthermore,...

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Bibliographic Details
Main Authors: Thomas Meyer, Mirjana Kessler, Christina Fotopoulou
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:International Journal of Molecular Sciences
Subjects:
serous ovarian cancer
fallopian tube
p53 signature
STIC
cellular transformation
cancer stem cells (CSC)
tumor microenvironment
Online Access:http://www.mdpi.com/1422-0067/14/4/6571

Internet

http://www.mdpi.com/1422-0067/14/4/6571

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