Loss of perilipin 2 in cultured myotubes enhances lipolysis and redirects the metabolic energy balance from glucose oxidation towards fatty acid oxidation
Lipid droplet (LD) coating proteins are essential for the formation and stability of intracellular LDs. Plin2 is an abundant LD coating protein in skeletal muscle, but its importance for muscle function is unclear. We show that myotubes established from Plin2−/− mice contain reduced content of LDs a...
Main Authors: | Yuan Z. Feng, Jenny Lund, Yuchuan Li, Irlin K. Knabenes, Siril S. Bakke, Eili T. Kase, Yun K. Lee, Alan R. Kimmel, G. Hege Thoresen, Arild Christian Rustan, Knut Tomas Dalen |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-11-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520338050 |
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