Shank3 Transgenic and Prenatal Zinc-Deficient Autism Mouse Models Show Convergent and Individual Alterations of Brain Structures in MRI

Shank3 Transgenic and Prenatal Zinc-Deficient Autism Mouse Models Show Convergent and Individual Alterations of Brain Structures in MRI

Research efforts over the past decades have unraveled both genetic and environmental factors, which contribute to the development of autism spectrum disorders (ASD). It is, to date, largely unknown how different underlying causes result in a common phenotype. However, the individual course of develo...

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Bibliographic Details
Main Authors: Michael Schoen, Harun Asoglu, Helen F. Bauer, Hans-Peter Müller, Alireza Abaei, Ann Katrin Sauer, Rong Zhang, Tian-jia Song, Juergen Bockmann, Jan Kassubek, Volker Rasche, Andreas M. Grabrucker, Tobias M. Boeckers
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Neural Circuits
Subjects:
ASD
autism mouse models
zinc deficiency
SHANK3
brain structures
animal MRI
Online Access:https://www.frontiersin.org/article/10.3389/fncir.2019.00006/full

Internet

https://www.frontiersin.org/article/10.3389/fncir.2019.00006/full

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