Randomized clinical trial: efficacy and safety of plecanatide in the treatment of chronic idiopathic constipation

Background: Plecanatide, with the exception of a single amino acid replacement, is identical to human uroguanylin and is approved in the United States for adults with chronic idiopathic constipation (CIC). This double-blind, placebo-controlled, phase III study evaluated the efficacy and safety of pl...

Full description

Bibliographic Details
Main Authors: Michael DeMicco, Laura Barrow, Bernadette Hickey, Kunwar Shailubhai, Patrick Griffin
Format: Article
Language:English
Published: SAGE Publishing 2017-11-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756283X17734697