A microRNA-7 binding site polymorphism in HOXB5 leads to differential gene expression in bladder cancer.

A microRNA-7 binding site polymorphism in HOXB5 leads to differential gene expression in bladder cancer.

PURPOSE: To investigate the biological function of HOXB5 in human bladder cancer and explore whether the HOXB5 3'-UTR SNP (1010A/G), which is located within the microRNA-7 binding site, was correlated with clinical features of bladder cancer. METHODS: Expression of HOXB5 in 35 human bladder can...

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Bibliographic Details
Main Authors: Junhua Luo, Qingqing Cai, Wei Wang, Hui Huang, Hong Zeng, Wang He, Weixi Deng, Hao Yu, Eddie Chan, Chi-fai Ng, Jian Huang, Tianxin Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3387002?pdf=render

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http://europepmc.org/articles/PMC3387002?pdf=render

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