p21WAF1/CIP1 Expression is Differentially Regulated by Metformin and Rapamycin
The mammalian target of rapamycin (mTOR) pathway plays an important role in the development of diabetic nephropathy and other age-related diseases. One of the features of DN is the elevated expression of p21WAF1/CIP1. However, the importance of the mTOR signalling pathway in p21 regulation is poorly...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2014-01-01
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Series: | International Journal of Chronic Diseases |
Online Access: | http://dx.doi.org/10.1155/2014/327640 |