Chromatin Loop Extrusion and Chromatin Unknotting

It has been a puzzle how decondensed interphase chromosomes remain essentially unknotted. The natural expectation is that in the presence of type II DNA topoisomerases that permit passages of double-stranded DNA regions through each other, all chromosomes should reach the state of topological equili...

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Bibliographic Details
Main Authors: Dusan Racko, Fabrizio Benedetti, Dimos Goundaroulis, Andrzej Stasiak
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Polymers
Subjects:
Online Access:http://www.mdpi.com/2073-4360/10/10/1126