The bone morphogenetic protein antagonist noggin protects white matter after perinatal hypoxia–ischemia
Hypoxia–ischemia (HI) in the neonate leads to white matter injury and subsequently cerebral palsy. We find that expression of bone morphogenetic protein 4 (BMP4) increases in the neonatal mouse brain after unilateral common carotid artery ligation followed by hypoxia. Since signaling by the BMP fami...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2011-06-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996111000441 |