p21 promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker
<p>Abstract</p> <p>The oncolytic adenovirus <it>dl</it>922-947 replicates selectively within and lyses cells with a dysregulated Rb pathway, a finding seen in > 90% human cancers. <it>dl</it>922-947 is more potent than wild type adenovirus and the E1B-del...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-07-01
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| Series: | Molecular Cancer |
| Online Access: | http://www.molecular-cancer.com/content/9/1/175 |