Acetylcholinesterase enzyme inhibitor activity of some novel pyrazinamide condensed 1,2,3,4-tetrahydropyrimidines

A new series of some novel pyrazinamide condensed 1,2,3,4-tetrahydropyrimidines was prepared by reacting of N-(3-oxobutanoyl)pyrazine-2-carboxamide with urea/thiourea and appropriate aldehyde in the presence of catalytic amount of laboratory made p-toluenesulfonic acid as an efficient catalyst. Conf...

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Bibliographic Details
Main Authors: Karthikeyan Elumalai, Mohammed Ashraf Ali, Manogaran Elumalai, Kalpana Eluri, Sivaneswari Srinivasan
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Biotechnology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X14000496