The Involvement of Ca2+ Signal Pathways in Distal Colonic Myocytes in a Rat Model of Dextran Sulfate Sodium-induced Colitis

The Involvement of Ca2+ Signal Pathways in Distal Colonic Myocytes in a Rat Model of Dextran Sulfate Sodium-induced Colitis

Background: Disrupted Ca2+ homeostasis contributes to the development of colonic dysmotility in ulcerative colitis (UC), but the underlying mechanisms are unknown. This study aimed to examine the alteration of colonic smooth muscle (SM) Ca2+ signaling and Ca2+ handling proteins in a rat model of dex...

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Bibliographic Details
Main Authors: Yan Wang, Jun-Xia Li, Guang-Ju Ji, Kui Zhai, Hua-Hong Wang, Xin-Guang Liu
Format: Article
Language:English
Published: Wolters Kluwer 2016-01-01
Series:Chinese Medical Journal
Subjects:
Calcium; Dextran Sulfate Sodium; Inositol 1,4,5-trisphosphate Receptor; Large-conductance Calcium-activated Potassium Channels; Phospholamban Protein; Sarcoplasmic Reticulum Calcium-transporting ATPase Calcium ATPase; Ulcerative Colitis
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=10;spage=1185;epage=1192;aulast=Wang

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http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=10;spage=1185;epage=1192;aulast=Wang

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