A framework for quantification and physical modeling of cell mixing applied to oscillator synchronization in vertebrate somitogenesis

In development and disease, cells move as they exchange signals. One example is found in vertebrate development, during which the timing of segment formation is set by a ‘segmentation clock’, in which oscillating gene expression is synchronized across a population of cells by Delta-Notch signaling....

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Bibliographic Details
Main Authors: Koichiro Uriu, Rajasekaran Bhavna, Andrew C. Oates, Luis G. Morelli
Format: Article
Language:English
Published: The Company of Biologists 2017-08-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/6/8/1235