Human gingival tissue-derived MSC suppress osteoclastogenesis and bone erosion via CD39-adenosine signal pathway in autoimmune arthritisResearch in context

Human gingival tissue-derived MSC suppress osteoclastogenesis and bone erosion via CD39-adenosine signal pathway in autoimmune arthritisResearch in context

Background: Bone destruction is one of many severe complications that occurs in patients with rheumatoid arthritis (RA) and current therapies are unable to cure this manifestation. This study here aims to determine whether GMSC can directly inhibit osteoclast formation and eventually attenuate osteo...

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Bibliographic Details
Main Authors: Yang Luo, Wenbin Wu, Jian Gu, Ximei Zhang, Junlong Dang, Julie Wang, Yongjiang Zheng, Feng Huang, Jia Yuan, Youqiu Xue, Qingling Fu, Umadevi Kandalam, Jacob Colello, Song Guo Zheng
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641930297X

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http://www.sciencedirect.com/science/article/pii/S235239641930297X

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