Osmoprotectants in Hybrid Liposome/HPMC Systems as Potential Glaucoma Treatment

The combination of acetazolamide-loaded nano-liposomes and Hydroxypropyl methylcellulose (HPMC) with similar components to the preocular tear film in an osmoprotectant media (trehalose and erythritol) is proposed as a novel strategy to increase the ocular bioavailability of poorly soluble drugs. Oph...

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Bibliographic Details
Main Authors: Miguel Gómez-Ballesteros, José Javier López-Cano, Irene Bravo-Osuna, Rocío Herrero-Vanrell, Irene Teresa Molina-Martínez
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/11/6/929