Hierarchical nanostructure and synergy of multimolecular signalling complexes
Imaging the nanostructure of signalling complexes in cells is challenging. Here, the authors present a multicolour, single-molecule, super-resolution approach with statistical tools to reveal a hierarchical topology and synergy of signalling complexes downstream of the T-cell receptor in fixed and l...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms12161 |