Protein disulphide isomerase inhibition as a potential cancer therapeutic strategy
Abstract The protein disulphide isomerase (PDI) gene family is a large, diverse group of enzymes recognised for their roles in disulphide bond formation within the endoplasmic reticulum (ER). PDI therefore plays an important role in ER proteostasis, however, it also shows involvement in ER stress, a...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-04-01
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Series: | Cancer Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/cam4.3836 |