Clec11a/osteolectin is an osteogenic growth factor that promotes the maintenance of the adult skeleton

Bone marrow stromal cells maintain the adult skeleton by forming osteoblasts throughout life that regenerate bone and repair fractures. We discovered that subsets of these stromal cells, osteoblasts, osteocytes, and hypertrophic chondrocytes secrete a C-type lectin domain protein, Clec11a, which pro...

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Bibliographic Details
Main Authors: Rui Yue, Bo Shen, Sean J Morrison
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/18782