Fluorescence-guided surgery of retroperitoneal-implanted human fibrosarcoma in nude mice delays or eliminates tumor recurrence and increases survival compared to bright-light surgery.

The aim of this study is to determine if fluorescence-guided surgery (FGS) can eradicate human fibrosarcoma growing in the retroperitoneum of nude mice. One week after retroperitoneal implantation of human HT1080 fibrosarcoma cells, expressing green fluorescent protein (GFP) (HT-1080-GFP), in nude m...

Full description

Bibliographic Details
Main Authors: Fuminari Uehara, Yukihiko Hiroshima, Shinji Miwa, Yasunori Tome, Shuya Yano, Mako Yamamoto, Yasunori Matsumoto, Hiroki Maehara, Kazuhiro Tanaka, Michael Bouvet, Fuminori Kanaya, Robert M Hoffman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4339719?pdf=render