Tissue Factor Knockdown in Porcine Islets: An Effective Approach to Suppressing the Instant Blood-Mediated Inflammatory Reaction

Tissue factor (TF) expression on islets has been shown to trigger instant blood-mediated inflammatory reaction (IBMIR), leading to rapid islet loss in portal vein islet transplantation. This study investigated whether antisense RNA-mediated TF gene knockdown in islets could suppress IBMIR as a strat...

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Bibliographic Details
Main Authors: Xiaoqian Ma, Bin Ye, Feng Gao, Qi Liang, Qiong Dong, Yin Liu, Pengfei Rong, Wei Wang M.D., Ph.D., Shounan Yi M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2012-02-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X580563