Tissue Factor Knockdown in Porcine Islets: An Effective Approach to Suppressing the Instant Blood-Mediated Inflammatory Reaction
Tissue factor (TF) expression on islets has been shown to trigger instant blood-mediated inflammatory reaction (IBMIR), leading to rapid islet loss in portal vein islet transplantation. This study investigated whether antisense RNA-mediated TF gene knockdown in islets could suppress IBMIR as a strat...
Main Authors: | Xiaoqian Ma, Bin Ye, Feng Gao, Qi Liang, Qiong Dong, Yin Liu, Pengfei Rong, Wei Wang M.D., Ph.D., Shounan Yi M.D., Ph.D. |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2012-02-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368911X580563 |
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