White matter hyperintensities in Parkinson's disease: do they explain the disparity between the postural instability gait difficulty and tremor dominant subtypes?

BACKGROUND: Brain white matter hyperintensities (WMHs) commonly observed on brain imaging of older adults are associated with balance and gait impairment and have also been linked to cognitive deficits. Parkinson's disease (PD) is traditionally sub-classified into the postural instability gait...

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Bibliographic Details
Main Authors: Talia Herman, Keren Rosenberg-Katz, Yael Jacob, Eitan Auriel, Tanya Gurevich, Nir Giladi, Jeffrey M Hausdorff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3561367?pdf=render