Bovine Leukemia Virus Small Noncoding RNAs Are Functional Elements That Regulate Replication and Contribute to Oncogenesis In Vivo.

Bovine Leukemia Virus Small Noncoding RNAs Are Functional Elements That Regulate Replication and Contribute to Oncogenesis In Vivo.

Retroviruses are not expected to encode miRNAs because of the potential problem of self-cleavage of their genomic RNAs. This assumption has recently been challenged by experiments showing that bovine leukemia virus (BLV) encodes miRNAs from intragenomic Pol III promoters. The BLV miRNAs are abundant...

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Bibliographic Details
Main Authors: Nicolas A Gillet, Malik Hamaidia, Alix de Brogniez, Gerónimo Gutiérrez, Nathalie Renotte, Michal Reichert, Karina Trono, Luc Willems
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4849745?pdf=render

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http://europepmc.org/articles/PMC4849745?pdf=render

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