Functional genomics indicates yeast requires Golgi/ER transport, chromatin remodeling, and DNA repair for low dose DMSO tolerance

Dimethyl sulfoxide (DMSO) is frequently utilized as a solvent in toxicological and pharmaceutical investigations. It is therefore important to establish the cellular and molecular targets of DMSO in order to differentiate its intrinsic effects from those elicited by a compound of interest. We perfor...

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Bibliographic Details
Main Authors: Brandon David Gaytán, Alex V Loguinov, Vanessa Yvette De La Rosa, Jan-Michael eLerot, Chris Dillon Vulpe
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00154/full