Prestin Contributes to Membrane Compartmentalization and Is Required for Normal Innervation of Outer Hair Cells

Prestin Contributes to Membrane Compartmentalization and Is Required for Normal Innervation of Outer Hair Cells

Outer hair cells (OHC) act as amplifiers and their function is modified by medial olivocochlear (MOC) efferents. The unique OHC motor protein, prestin, provides the molecular basis for somatic electromotility, which is required for sensitivity and frequency selectivity, the hallmarks of mammalian he...

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Bibliographic Details
Main Authors: Satoe Takahashi, Willy Sun, Yingjie Zhou, Kazuaki Homma, Bechara Kachar, Mary Ann Cheatham, Jing Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
prestin
outer hair cells
efferent innervation
PMCA2
KCNQ4
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00211/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00211/full

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