Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368

Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368

Abstract Background Reperfusion ventricular arrhythmia (RA) associated with hypothermic ischaemic storage is increasingly recognized as a substantial contributor to adverse consequences after heart transplantation. Ischemia- or hypothermia-induced gap junction (GJ) remodelling is closely linked to R...

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Bibliographic Details
Main Authors: Wei Chao Li, Hong Gao, Ju Gao, Zi Jun Wang
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Anesthesiology
Subjects:
Sevoflurane
Gap junction remodelling
Cx43 phosphorylation at Ser368
Reperfusion ventricular arrhythmia
Hypothermic ischaemic storage
Online Access:http://link.springer.com/article/10.1186/s12871-018-0656-8

Internet

http://link.springer.com/article/10.1186/s12871-018-0656-8

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