Dose-Dependent Effects of Long-Term Administration of Hydrogen Sulfide on Myocardial Ischemia–Reperfusion Injury in Male Wistar Rats: Modulation of RKIP, NF-κB, and Oxidative Stress

Dose-Dependent Effects of Long-Term Administration of Hydrogen Sulfide on Myocardial Ischemia–Reperfusion Injury in Male Wistar Rats: Modulation of RKIP, NF-κB, and Oxidative Stress

Decreased circulating levels of hydrogen sulfide (H<sub>2</sub>S) are associated with higher mortality following myocardial ischemia. This study aimed at determining the long-term dose-dependent effects of sodium hydrosulfide (NaSH) administration on myocardial ischemia-reperfusion (IR)...

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Bibliographic Details
Main Authors: Sajad Jeddi, Sevda Gheibi, Khosrow Kashfi, Mattias Carlström, Asghar Ghasemi
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
hydrogen sulfide
nitric oxide
infarct size
ischemia–reperfusion injury
h<sub>2</sub>s-producing enzymes
no-producing enzymes
rkip
nf-κb
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/21/4/1415

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https://www.mdpi.com/1422-0067/21/4/1415

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