DOMINO: a network‐based active module identification algorithm with reduced rate of false calls

Abstract Algorithms for active module identification (AMI) are central to analysis of omics data. Such algorithms receive a gene network and nodes' activity scores as input and report subnetworks that show significant over‐representation of accrued activity signal (“active modules”), thus repre...

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Bibliographic Details
Main Authors: Hagai Levi, Ran Elkon, Ron Shamir
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20209593