Multitasking guardian of mitochondrial quality: Parkin function and Parkinson’s disease

Abstract The familial form of Parkinson’s disease (PD) is linked to mutations in specific genes. The mutations in parkin are one of the most common causes of early-onset PD. Mitochondrial dysfunction is an emerging active player in the pathology of neurodegenerative diseases, because mitochondria ar...

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Bibliographic Details
Main Authors: Iryna Kamienieva, Jerzy Duszyński, Joanna Szczepanowska
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Translational Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s40035-020-00229-8