IL-4 Receptor α Chain Protects the Kidney Against Tubule-Interstitial Injury Induced by Albumin Overload

IL-4 Receptor α Chain Protects the Kidney Against Tubule-Interstitial Injury Induced by Albumin Overload

Increasing evidence has highlighted the role of tubule-interstitial injury (TII) as a vital step in the pathogenesis of acute kidney injury (AKI). Incomplete repair of TII during AKI could lead to the development of chronic kidney disease. Changes in albumin endocytosis in proximal tubule epithelial...

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Bibliographic Details
Main Authors: Diogo B. Peruchetti, João Luiz Silva-Filho, Rodrigo P. Silva-Aguiar, Douglas E. Teixeira, Christina M. Takiya, Mariana C. Souza, Maria das Graças Henriques, Ana Acacia S. Pinheiro, Celso Caruso-Neves
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Physiology
Subjects:
IL-4
tubule-interstitial injury
albumin overload
renal disease
proteinuria
albumin endocytosis
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00172/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00172/full

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