Aberrant DNA damage response pathways may predict the outcome of platinum chemotherapy in ovarian cancer.

Aberrant DNA damage response pathways may predict the outcome of platinum chemotherapy in ovarian cancer.

Ovarian carcinoma (OC) is the most lethal gynecological malignancy. Despite the advances in the treatment of OC with combinatorial regimens, including surgery and platinum-based chemotherapy, patients generally exhibit poor prognosis due to high chemotherapy resistance. Herein, we tested the hypothe...

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Bibliographic Details
Main Authors: Dimitra T Stefanou, Aristotelis Bamias, Hara Episkopou, Soterios A Kyrtopoulos, Maria Likka, Theodore Kalampokas, Stylianos Photiou, Nikos Gavalas, Petros P Sfikakis, Meletios A Dimopoulos, Vassilis L Souliotis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4320060?pdf=render

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http://europepmc.org/articles/PMC4320060?pdf=render

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